The Difference Between Actin and Myosin
Despite extensive studies, the molecular mechanism of myosin head conformational changes still remains to be a matter for debate and speculation.
They are also responsible for both cellular movements and non-cellular movements. The main difference between actin and myosin is that actin is a protein that produces thin contractile filaments within muscle cells, whereas myosin is a protein that produces the dense contractile filaments within muscle cells.
To overcome these limitations, we have devised methods of image restoration and generalized correlation averaging, and applied them to cryosections of rabbit psoas fibers in both the relaxed and rigor states (Huxley, H. E., and J. Hanson. 1954).
Huxley, H. E., and J. Hanson. 1954. Changes in the cross-striations of muscle during contraction and stretch and their structural
interpretation. Nature (Lond.). 173:973-976.
Squire, J. M. 1981. The Structural basis of Muscular Contraction. Plenum Publishing Corp., New York. 8-16, 524-527.
Pollard, T. D. 1987. The myosin crossbridge problem. Cell. 48:909-910.