Metoprolol: The Benefit of the Drug and the Indication and the Action of Drug
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However, other factors affect drug response as well. Density of receptors on the cell surface, the mechanism by which a signal is transmitted into the cell by second messengers (substances within the cell), or regulatory factors that control gene translation and protein production may influence drug effect.
Current uses of β-blockers in CDs include ischemic heart diseases, hypertension, cardiac arrhythmias, and heart failure.
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